Day: 5 October 2021
vs 
Buxton vs Whitby Town
vs 
Stalybridge Celtic vs Grantham Town
vs 
Witton Albion vs Hyde United
vs 
Lancaster City FC vs Stafford Rangers
vs 
Bamber Bridge vs South Shields
vs 
Basford United vs FC United of Manchester
vs 
Morpeth Town vs Radcliffe FC
vs 